Pulmonary involvement in Niemann-Pick type B disease.
نویسندگان
چکیده
Bone marrow biopsy showed infiltration by numerous histiocytes. Some of the histiocytes contained vacuolated cytoplasm whilst others contained granules that stained deep blue with the May-Grünwald-Giemsa stain (Figure 2). This histological pattern was indicative of Niemann-Pick disease. Confirmation of this diagnosis was obtained by lysosomal enzyme assay that showed undetectable sphingomyelinase activity. Histological examination of the pulmonary biopsy speciImages in Radiology www.jpgmonline.com
منابع مشابه
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ورودعنوان ژورنال:
- Journal of postgraduate medicine
دوره 50 4 شماره
صفحات -
تاریخ انتشار 2004